This study presents development of temazepam tablets, which could provide rapid disintegration and immediate release of drug in oral cavity. Tablets were prepared by using direct compression method with different super disintegrants like Sodium starch glycolate, Croscarmellose sodium, and Crospovidone.        The prepared tablets were evaluated for hardness, thickness, weight variation, percentage friability, wetting time, disintegration time and in vitro studies.Thein vitro drug release study was carried out for 15 min. Among all formulations, the formulation of F₁ (98.15%) oral dispersible tablets has been showed better release of dosage forms.

Diclofenac Diethylamine shows therapeutic value against various disease conditions. The present study is to determine the possibility of developing fingerprint characteristic of diclofenac diethylamine by using different solvent  systems such as coconut oil, glycerol, propylene glycol, sesame oil, 2-propanol,benzyl alcohol, chromophore RH 40 for the preparation of topical formulations such as cream, gels etc. identification of functional groups frequencies with the help of fourier transform infrared spectroscopy has been made for the solvent suitability of diclofenac diethylamine with suitable solvent were studied for the topical gel formulation. From FTIR (400 cm‾¹ to 4000 cm‾¹ region) spectroscopic studies were carried out and spectrum were used for identification for invitro drug and solvents compatibility study. Among this study only one solvent not suitable with diclofenac diethylamine such as benzyl alcohol due to the additional peaks observed in the spectrum combination (1871, 1842, and 1811cm^-1).

An accurate, simple and sensitive spectrophotometric method was developed for determination of pantoprazole sodium in bulk and pharmaceutical dosage form. The method was based on the reaction of the drug with 2, 4- dinitrofluorobenzene through nucleophilic substitution reaction, producing yellow colored product measured atλ_max431 nm. Beer’s law was obeyed in the concentration range from (10- 50 µg ml^-1) with molar absorpitivity 6.823 x 10³ Lmol^-1cm^-1.

India is considered to be the home of many medicinally important plant species. The present study was aimed to evaluate the antimicrobial activity of Vetiveria lawsonii(Family-Poaceae). The ethanol extract was prepared by Soxhlet extraction. The qualitative screening of the plant revealed that the presence of Alkaloids, Flavonoids, Terpenoids, Steroids, Carbohydrates, Glycosides, Saponins, Phytosterols and Proteins. The ethanol extract of Vetiveria lawsonii showing high antimicrobial activity against the microbes revealed by Agar well diffusion method. Hence, we can conclude that the ethanol extracts of Vetiveria lawsonii was possess antimicrobial activity.

Residual solvents (RS) are volatile organic chemicals that are used during the manufacturing process of pharmaceuticals. They are classified into three categories according to their toxicity potential. The Class 1 residual solvents include the compounds considered to be the most toxic. A simple chromatographic method has been developed for the determination of tested Class 1 residual solvents (1,1-dichloroethene, 1,2-dichloroethane, 1,1,1-trichloroethane, carbon tetrachloride and benzene) in typical organic diluents like DMSO, DMF, DMA. The analytes separation was obtained on DB-624 and DB-WAX columns. The developed gas chromatographic method offers peak shape, good resolution and reasonable retention times for all the solvents.